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  Nivaliln (Galantamine)
 Nivalin introduction
 Nivalin is the result of a natural product
 Nivalin and the adrenals
 Nivalin pharmacokinetics
 Safety and Toxicity studies
 Mutagenicity of Nivalin
 Clinical application of Nivalin
 References
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Nivalin (Galantamine) is an original phytopreparation developed by Sopharma's own research team and produced with an original technology for extraction of the alkaloid Galantamine from the bulbs of the plant snowdrops (Leucojum aestivum).
 
 
 
 
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Nivalin references  
 
  1. Mayrhofer, O. Nivalin - Experience with application of galantamine as an antagonist to the relaxants of curare type. The bulleting of the Swiss Academy of Medical Sciences, vol. 23, 1967, fasc. 1/2 pp. 48.52
  2. Stoyanov, E.A. Der Anaesthesist, 1964, 13(7), 217-220
  3. Paskov, D.S. Nivalin: phramacology and clinical application, Medicina i Fizkultura, Sofia, 1959.
  4. Paskov, D.S., K.A. Stoyanov, S.K. Saev, K.A. Tenev, M.L. Mincheva. Clinical experience with Nivalin as anticholinesterase drug in anaesthesiological practice. Proc. First Eur. Congress of Anesthesiology, 3-9 Sept., Vienna, 1962.
  5. Cozanitis, D.A., P.A. Rosenberg. Preliminary experiments with Galanthamine Hydrobromide on depressed respiration. Anesthesiologist, 1974.
  6. Neumenko, E.V. A propos of the mechanism of Nivalin effect upon the hypophyseal-adrenal system. Pharm. Toxicol. 1965, 28(6), 659-62 (in Russian).
  7. Cozanitis, D.A. Galanthamine hydrobromide versus neostigmine. A plasma cortisol study in men. Anaesthesia, 1974, 29, 163-168.
  8. Milstein,, G.I. Use of preparation with anticholinesterase activity for coping with the disorders. Zh. Neuropat. Psychiatr., 1968, 68(6), 913-916 (in Russian).
  9. Popova, E.N., N.N. Bobolepov. A propos of Nivalin effect upon neuronal structures with different cytoarchitectonic formation. Neurol. Psychiatr. Neurosurg., 1966, 5(1), 12-18.
  10. Stanchev, B.D., T.S. Takeva. Nivalin and phagocytosis, Hyg. Epidem. Microbiol., 1959.
  11. Michailova, D., I.Yamboliev, Z. Zhivkova, J.Tencheva, V.Jovovich. Pharmacokinetics of galanthamine hydrobromide after single subcutaneous and oral dosage in humans. Pharmacology, 1989, 50-58.
  12. Stoyanov, E. Clinical use of Nivalin in decurarization (a six year experience). Anaesthesia Reanim., 1971, 3(1), 17-23.
  13. Nastev, G. et al. Nivalin treatment of patients with diseases of nervous system. Cultura Med. (Roma), 1960, 15, 87-97.
 
 
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